Synapse and gene products (Gulsuner et al. 2020)
Fig. 4: Synaptic genes harboring damaging mutations in Xhosa persons with schizophrenia.
Proteins shown in the figure are encoded by genes that are mutant in at least one individual with schizophrenia. Synaptic genes collectively harbor a significantly greater burden of private damaging mutations in cases compared with controls. No single gene is significantly enriched for private damaging events in cases; most genes have a private damaging variant in one case and no controls.